The proteolipid protein promoter drives expression outside of the oligodendrocyte lineage during embryonic and early postnatal development.

The proteolipid protein (Plp) gene promoter is responsible for driving expression of one of the major components of myelin--PLP and its splice variant DM-20. Both products are classically thought to express predominantly in oligodendrocytes. However, accumulating evidence suggests Plp expression is...

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Bibliographic Details
Main Authors: John-Paul Michalski, Carrie Anderson, Ariane Beauvais, Yves De Repentigny, Rashmi Kothary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21572962/?tool=EBI