Progress in quickly finding orthologs as reciprocal best hits: comparing blast, last, diamond and MMseqs2

Abstract Background Finding orthologs remains an important bottleneck in comparative genomics analyses. While the authors of software for the quick comparison of protein sequences evaluate the speed of their software and compare their results against the most usual software for the task, it is not c...

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Bibliographic Details
Main Authors: Julie E. Hernández-Salmerón, Gabriel Moreno-Hagelsieb
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-07132-6