A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium.

Interleukin (IL) 33, a member of IL-1 cytokine family, is well known to promote Th2 type immune responses by signaling through its receptor ST2. However, it is not clear whether ST2 is expressed by mucosal epithelium, and how it responds to IL-33 to induce inflammatory mediators. This study was to i...

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Bibliographic Details
Main Authors: Jing Lin, Lili Zhang, Guiqiu Zhao, Zhitao Su, Ruzhi Deng, Stephen C Pflugfelder, De-Quan Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3622010?pdf=render