All-<it>trans </it>retinoic acid induces COX-2 and prostaglandin E<sub>2 </sub>synthesis in SH-SY5Y human neuroblastoma cells: involvement of retinoic acid receptors and extracellular-regulated kinase 1/2

<p>Abstract</p> <p>Background</p> <p>Our recent results show that all-<it>trans </it>retinoic acid (ATRA), an active metabolite of vitamin A, induces COX-dependent hyperalgesia and allodynia in rats. This effect was mediated by retinoic acid receptors (RARs)...

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Bibliographic Details
Main Authors: Lucio-Cazana Francisco, Herrero Juan F, Alique Matilde
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/1