Regulation of ADAM10 by MicroRNA-23a Contributes to Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice

Regulation of ADAM10 by MicroRNA-23a Contributes to Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice

ADAM10, a member of the disintegrin and metalloproteinase domain-containing protein (ADAM) family, has been reported to mediate proteolytic shedding of cell surface proteins. An increasing body of evidence indicates that ADAM10 is involved in various neurological disorders including epilepsy. Howeve...

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Bibliographic Details
Main Authors: Xinjian Zhu, Yuanyuan Yao, Yaoyao Liu, Rong Zhou, Wei Zhang, Qiang Hu, Hang Liu, Mohammed Hidayath Al Hamda, Aifeng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ADAM10
microRNA-23a
hippocampus
status epilepticus
epileptogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00180/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00180/full

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