A study on OPG/RANK/RANKL axis in osteoporotic bile duct-ligated rats and the involvement of nitrergic and opioidergic systems

A study on OPG/RANK/RANKL axis in osteoporotic bile duct-ligated rats and the involvement of nitrergic and opioidergic systems

Chronic liver disease (CLD) affects millions of people and its impact on bone loss has become a subject of interest. Nitric oxide and endogenous opioids are suggested to increase during cholestasis/cirrhosis and may impact bone resorption by different mechanisms. The receptor activator of nuclear fa...

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Bibliographic Details
Main Authors: Amir Hossein Doustimotlagh, Ahmad Reza Dehpour, Shahroo Etemad-Moghadam, Mojgan Alaeddini, Sattar Ostadhadi, Abolfazl Golestani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
cirrhosis; bone loss; nitrergic system; opioidergic system; bdl rats; rank/rankl/opg axis
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=3;spage=239;epage=249;aulast=Doustimotlagh

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=3;spage=239;epage=249;aulast=Doustimotlagh

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