Vaccination with DNA encoding truncated enterohemorrhagic Escherichia coli (EHEC) factor for adherence-1 gene (efa-1’) confers protective immunity to mice infected with E. coli O157:H7

Vaccination with DNA encoding truncated enterohemorrhagic Escherichia coli (EHEC) factor for adherence-1 gene (efa-1’) confers protective immunity to mice infected with E. coli O157:H7

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is the predominant causative agent of hemorrhagic colitis in humans and is the cause of haemolytic uraemic syndrome and other illnesses. Cattle have been implicated as the main reservoir of this organism. Here, we evaluated the immunogenicity and p...

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Bibliographic Details
Main Authors: Roberto eRiquelme-Neira, Alejandra eRivera, Darwin eSaez, Pablo eFernández, Felipe eDel Canto, Juan Carlos Salazar, Gonzalo eOsorio, Roberto Mauricio Vidal, Angel eOñate
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
DNA vaccine
O157:H7 serotype
truncated efa-1 gene
enterohemorragic E.coli
protective to mice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00104/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00104/full

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