Treatment with pCramoll Alone and in Combination with Fluconazole Provides Therapeutic Benefits in C. gattii Infected Mice

Treatment with pCramoll Alone and in Combination with Fluconazole Provides Therapeutic Benefits in C. gattii Infected Mice

Cryptococcus gattii is one of the main causative agents of cryptococcosis in immunocompetent individuals. Treatment of the infection is based on the use of antimycotics, however, the toxicity of these drugs and the increase of drug-resistant strains have driven the search for more effective and less...

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Bibliographic Details
Main Authors: Jannyson J. Jandú, Marliete C. Costa, Julliana R. A. Santos, Fernanda M. Andrade, Thais F. Magalhães, Márcia V. Silva, Maria C. A. B. Castro, Luanna C. B. B. Coelho, Aline G. Gomes, Tatiane A. Paixão, Daniel A. Santos, Maria T. S. Correia
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
cryptococcosis
immunomodulation
lectins
Cratylia mollis lectin
fluconazole
survival
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00211/full

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http://journal.frontiersin.org/article/10.3389/fcimb.2017.00211/full

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