On the Use of Min-Max Combination of Biomarkers to Maximize the Partial Area under the ROC Curve

Background. Evaluation of diagnostic assays and predictive performance of biomarkers based on the receiver operating characteristic (ROC) curve and the area under the ROC curve (AUC) are vital in diagnostic and targeted medicine. The partial area under the curve (pAUC) is an alternative metric focus...

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Bibliographic Details
Main Authors: Hua Ma, Susan Halabi, Aiyi Liu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Probability and Statistics
Online Access:http://dx.doi.org/10.1155/2019/8953530