Novel Pathway of Adenosine Generation in the Lungs from NAD<sup>+</sup>: Relevance to Allergic Airway Disease

Adenosine and uric acid (UA) play a pivotal role in lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). In the present experiments, we measured adenosine synthesis from nicotinamide adenine dinucleotide (NAD<sup>+</sup>) in membranes prepared from wild type (WT...

Full description

Bibliographic Details
Main Authors: Richard Graeff, Alonso Guedes, Ruth Quintana, Erin Wendt-Hornickle, Caroline Baldo, Timothy Walseth, Scott O’Grady, Mathur Kannan
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/21/4966