Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism.

Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism.

Infection with dengue viruses (DENV) leads to a spectrum of disease outcomes. The pathophysiology of severe versus non-severe manifestations of DENV infection may be driven by host responses, which could be reflected in the transcriptional profiles of peripheral blood immune cells.We conducted genom...

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Bibliographic Details
Main Authors: P'ng Loke, Samantha N Hammond, Jacqueline M Leung, Charles C Kim, Sajeev Batra, Crisanta Rocha, Angel Balmaseda, Eva Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2886038?pdf=render

Internet

http://europepmc.org/articles/PMC2886038?pdf=render

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