Hirschsprung´s Disease—Recent Understanding of Embryonic Aspects, Etiopathogenesis and Future Treatment Avenues
Hirschsprung´s disease is a neurocristopathy, caused by defective migration, proliferation, differentiation and survival of neural crest cells, leading to gut aganglionosis. It usually manifests rapidly after birth, affecting 1 in 5000 live births around the globe. In recent decades, there has been...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Medicina |
Subjects: | |
Online Access: | https://www.mdpi.com/1010-660X/56/11/611 |