Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells

Abstract Background Retinoic acid (RA) signaling has been identified as a key driver in male and female gamete development. The presence of RA is a critical step in the initiation of meiosis and is required for the production of competent oocytes from primordial germ cells. Meiosis has been identifi...

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Bibliographic Details
Main Authors: Paul W. Dyce, Neil Tenn, Gerald M. Kidder
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Ovarian Research
Online Access:http://link.springer.com/article/10.1186/s13048-018-0390-3