High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer

DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC). Its DNA amplification is often part of the targeted DNA-sequencing p...

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Bibliographic Details
Main Authors: Eriko Katsuta, Li Yan, Takashi Takeshita, Kerry-Ann McDonald, Subhamoy Dasgupta, Mateusz Opyrchal, Kazuaki Takabe
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
myc
Online Access:https://www.mdpi.com/1422-0067/21/1/217