Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil: formulation, characterization and in vitro drug release studies

Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil: formulation, characterization and in vitro drug release studies

Abstract Candesartan cilexetil is an ester prodrug antagonist to angiotensin II receptor type 1 (AT1) used in management of many cardiovascular diseases. The absolute bioavailability of candesartan cilexetil is about (14–40%). Therefore, the paper aim was to prepare and evaluate solid self-nanoemuls...

Full description

Bibliographic Details
Main Authors: Halah Hussein Ali, Ahmed Abbas Hussein
Format: Article
Language:English
Published: SpringerOpen 2017-06-01
Series:AAPS Open
Subjects:
Candesartan cilexetil
Solubility
Pseudo-ternary phase diagram
Adsorbent mixture
Self-nanoemulsifying drug delivery system
Stability
Online Access:http://link.springer.com/article/10.1186/s41120-017-0015-8

Internet

http://link.springer.com/article/10.1186/s41120-017-0015-8

Similar Items