Single-molecule visualization of dynamic transitions of pore-forming peptides among multiple transmembrane positions

Single-molecule visualization of dynamic transitions of pore-forming peptides among multiple transmembrane positions

Assessing protein localization within lipid membranes is problematic. Here, the authors describe a single molecule visualization method based on surface-induced fluorescence attenuation (SIFA) to determine the insertion depth and lateral diffusion of a peptide in a lipid bilayer.

Bibliographic Details
Main Authors: Ying Li, Zhenyu Qian, Li Ma, Shuxin Hu, Daguan Nong, Chunhua Xu, Fangfu Ye, Ying Lu, Guanghong Wei, Ming Li
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12906

Internet

https://doi.org/10.1038/ncomms12906

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