TSA protects H9c2 cells against thapsigargin-induced apoptosis related to endoplasmic reticulum stress-mediated mitochondrial injury

Endoplasmic reticulum stress (ERS) activates an adaptive unfolded protein response (UPR) that facilitates cellular repair, however, under prolonged ER stress, the UPR can ultimately trigger apoptosis thereby terminating damaged cells. Recently, TSA has shown protective effects on ERS and its mechani...

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Bibliographic Details
Main Authors: Zhiping Li, Yan Liu, Xinlun Dai, Qiangqiang Zhou, Xueli Liu, Zeyu Li, Xia Chen
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417300932