Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice

Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice

Organophosphate pesticides and nerve agents (OPs), are characterized by cholinesterase inhibition. In addition to severe peripheral symptoms, high doses of OPs can lead to seizures and status epilepticus (SE). Long lasting seizure activity and subsequent neurodegeneration promote neuroinflammation l...

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Bibliographic Details
Main Authors: Clémence Maupu, Julie Enderlin, Alexandre Igert, Myriam Oger, Stéphane Auvin, Rahma Hassan-Abdi, Nadia Soussi-Yanicostas, Xavier Brazzolotto, Florian Nachon, Grégory Dal Bo, Nina Dupuis
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Neurobiology of Disease
Subjects:
Astrocyte
Microglia
Cytokines
Seizure
DFP
Organophosphates
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000255

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http://www.sciencedirect.com/science/article/pii/S0969996121000255

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