Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

Summary: Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease modeling and the generation of tissue for renal replacement. Long-term application, however, will require transferability between hPSC lines and significant improvements in organ maturation. A key question is...

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Bibliographic Details
Main Authors: Cathelijne W. van den Berg, Laila Ritsma, M. Cristina Avramut, Loes E. Wiersma, Bernard M. van den Berg, Daniëlle G. Leuning, Ellen Lievers, Marije Koning, Jessica M. Vanslambrouck, Abraham J. Koster, Sara E. Howden, Minoru Takasato, Melissa H. Little, Ton J. Rabelink
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300675

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http://www.sciencedirect.com/science/article/pii/S2213671118300675

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