Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing.

Spermatogenesis is the process by which male gametes are formed from a self-renewing population of spermatogonial stem cells (SSCs) residing in the testis. SSCs represent less than 1% of the total testicular cell population in adults, but must achieve a stable balance between self-renewal and differ...

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Bibliographic Details
Main Authors: Kathryn J Grive, Yang Hu, Eileen Shu, Andrew Grimson, Olivier Elemento, Jennifer K Grenier, Paula E Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6443194?pdf=render