Thymoquinone-Induced Reactivation of Tumor Suppressor Genes in Cancer Cells Involves Epigenetic Mechanisms

The epigenetic silencing of tumor suppressor genes (TSGs) is a common finding in several solid and hematological tumors involving various epigenetic readers and writers leading to enhanced cell proliferation and defective apoptosis. Thymoquinone (TQ), the major biologically active compound of black...

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Bibliographic Details
Main Authors: Shahad A Qadi, Mohammed A Hassan, Ryan A Sheikh, Othman AS Baothman, Mazin A Zamzami, Hani Choudhry, Abdulrahman Labeed Al-Malki, Ashwag Albukhari, Mahmoud Alhosin
Format: Article
Language:English
Published: SAGE Publishing 2019-04-01
Series:Epigenetics Insights
Online Access:https://doi.org/10.1177/2516865719839011