Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells

Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells

Honokiol is a natural compound with small molecular structure and extracted from bark of magnolia trees. The biological activities of honokiol include anti-oxidation, anti-inflammation as well as anti-tumor. However, their mechanism remains unknown. In this study, A549 cell line and EGFR-mutant cell...

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Bibliographic Details
Main Authors: Xi Dai, Run-Ze Li, Ze-Bo Jiang, Chun-Li Wei, Lian-Xiang Luo, Xiao-Jun Yao, Guo-Ping Li, Elaine L.-H. Leung
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
honokiol
Lyn kinase
EGFR
apoptosis
Lung cancer
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00558/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00558/full

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