NR2B receptor blockade inhibits pain-related sensitization of amygdala neurons

<p>Abstract</p> <p>Pain-related sensitization and synaptic plasticity in the central nucleus of the amygdala (CeA) depend on the endogenous activation of NMDA receptors and phosphorylation of the NR1 subunit through a PKA-dependent mechanism. Functional NMDA receptors are heteromer...

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Bibliographic Details
Main Authors: Neugebauer Volker, Horváth Csilla, Ji Guangchen
Format: Article
Language:English
Published: SAGE Publishing 2009-04-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/21