Purinergic control of inflammation and thrombosis: Role of P2X1 receptors

Purinergic control of inflammation and thrombosis: Role of P2X1 receptors

Inflammation shifts the hemostatic mechanisms in favor of thrombosis. Upon tissue damage or infection, a sudden increase of extracellular ATP occurs, that might contribute to the crosstalk between inflammation and thrombosis. On platelets, P2X1 receptors act to amplify platelet activation and aggreg...

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Bibliographic Details
Main Authors: Cécile Oury, Christelle Lecut, Alexandre Hego, Odile Wéra, Céline Delierneux
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Thrombosis
Inflammation
P2X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S200103701400049X

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http://www.sciencedirect.com/science/article/pii/S200103701400049X

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