Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole.

Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole.

Mitochondrial dysfunction has been implicated in rare and common forms of type 2 diabetes (T2DM). Additionally, rare mitochondrial DNA (mtDNA) mutations have been shown to be causal for T2DM pathogenesis. So far, many studies have investigated the possibility that mtDNA variation might affect the ri...

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Bibliographic Details
Main Authors: Alessandro Achilli, Anna Olivieri, Maria Pala, Baharak Hooshiar Kashani, Valeria Carossa, Ugo A Perego, Francesca Gandini, Aurelia Santoro, Vincenza Battaglia, Viola Grugni, Hovirag Lancioni, Cristina Sirolla, Anna Rita Bonfigli, Antonella Cormio, Massimo Boemi, Ivano Testa, Ornella Semino, Antonio Ceriello, Liana Spazzafumo, Maria Nicola Gadaleta, Maurizio Marra, Roberto Testa, Claudio Franceschi, Antonio Torroni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3111471?pdf=render

Internet

http://europepmc.org/articles/PMC3111471?pdf=render

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