OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids[S]

Oxysterol binding protein-related protein 2 (ORP2) is a member of the oxysterol binding protein family, previously shown to bind 25-hydroxycholesterol and implicated in cellular cholesterol metabolism. We show here that ORP2 also binds 22(R)-hydroxycholesterol [22(R)OHC], 7-ketocholesterol, and chol...

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Bibliographic Details
Main Authors: Riikka Hynynen, Monika Suchanek, Johanna Spandl, Nils Ba¨ck, Christoph Thiele, Vesa M. Olkkonen
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307793