Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy

Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy

The majority of anticancer drugs have poor aqueous solubility, produce adverse effects in healthy tissue, and thus impose major limitations on both clinical efficacy and therapeutic safety of cancer chemotherapy. To help circumvent problems associated with solubility, most cancer drugs are now formu...

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Bibliographic Details
Main Authors: Sonja Dragojevic, Jung Su Ryu, Drazen Raucher
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
polymer based prodrugs
anticancer drugs
macromolecules
drug delivery
cancer therapy
genetically engineered biopolymers
synthetic and natural polymers
Online Access:http://www.mdpi.com/1420-3049/20/12/19804

Internet

http://www.mdpi.com/1420-3049/20/12/19804

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