Impact of Nox5 polymorphisms on basal and stimulus-dependent ROS generation.

Nox5 is an EF-hand containing, calcium-dependent isoform of the NADPH oxidase family of reactive oxygen species (ROS) generating enzymes. Altered expression and activity of Nox5 has been reported in cardiovascular diseases and cancers but the absence of Nox5 in rodents has precluded a greater unders...

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Bibliographic Details
Main Authors: Yusi Wang, Feng Chen, Brian Le, David W Stepp, David J R Fulton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081039?pdf=render