Cerebellar Cells Self-Assemble into Functional Organoids on Synthetic, Chemically Crosslinked ECM-Mimicking Peptide Hydrogels

Cerebellar Cells Self-Assemble into Functional Organoids on Synthetic, Chemically Crosslinked ECM-Mimicking Peptide Hydrogels

Hydrogel-supported neural cell cultures are more in vivo-relevant compared to monolayers formed on glass or plastic substrates. However, there is a lack of synthetic microenvironment available for obtaining standardized and easily reproducible cultures characterized by tissue-mimicking cell composit...

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Bibliographic Details
Main Authors: Zbigniev Balion, Vytautas Cėpla, Nataša Svirskiene, Gytis Svirskis, Kristina Druceikaitė, Hermanas Inokaitis, Justina Rusteikaitė, Ignas Masilionis, Gintarė Stankevičienė, Tadas Jelinskas, Arturas Ulčinas, Ayan Samanta, Ramūnas Valiokas, Aistė Jekabsone
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
collagen-like peptide
collagen mimetic peptide
RGD
hydrogel
neurons
astrocytes
Online Access:https://www.mdpi.com/2218-273X/10/5/754

Internet

https://www.mdpi.com/2218-273X/10/5/754

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