APC/CFZR-1 Controls SAS-5 Levels To Regulate Centrosome Duplication in Caenorhabditis elegans

As the primary microtubule-organizing center, centrosomes play a key role in establishing mitotic bipolar spindles that secure correct transmission of genomic content. For the fidelity of cell division, centrosome number must be strictly controlled by duplicating only once per cell cycle. Proper lev...

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Bibliographic Details
Main Authors: Jeffrey C. Medley, Lauren E. DeMeyer, Megan M. Kabara, Mi Hye Song
Format: Article
Language:English
Published: Oxford University Press 2017-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300260