Single-lesion Prostate-specific Membrane Antigen Protein Expression (PSMA) and Response to [177Lu]-PSMA-ligand Therapy in Patients with Castration-resistant Prostate Cancer

Single-lesion Prostate-specific Membrane Antigen Protein Expression (PSMA) and Response to [177Lu]-PSMA-ligand Therapy in Patients with Castration-resistant Prostate Cancer

Initial reports of a clinical response in patients treated with the radioligand [177Lu]-PSMA-617 for castration-resistant prostate cancer (CRPC) are promising, despite known inter- and intrapatient heterogeneity. In metastatic CRPC, we examined the association of baseline immunohistochemical (IHC) e...

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Bibliographic Details
Main Authors: Judith Stangl-Kremser, Sazan Rasul, Jeffrey J. Tosoian, Simpa S. Salami, Alexander Zaslavsky, Aaron Udager, Peter Mazal, Renate Kain, Eva Comperat, Marcus Hacker, Alexander Haug, Markus Mitterhauser, Carmen Pozo-Salido, Christina Steinbach, Melanie R. Hassler, Gero Kramer, Shahrokh F. Shariat, Ganesh S. Palapattu
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:European Urology Open Science
Subjects:
Biomarker
Prostate cancer
Prostate-specific membrane antigen
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168321001178

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http://www.sciencedirect.com/science/article/pii/S2666168321001178

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