Properdin Deficiency Impairs Phagocytosis and Enhances Injury at Kidney Repair Phase Post Ischemia–Reperfusion

Properdin Deficiency Impairs Phagocytosis and Enhances Injury at Kidney Repair Phase Post Ischemia–Reperfusion

Properdin, a positive regulator of complement alternative pathway, participates in renal ischemia–reperfusion (IR) injury and also acts as a pattern-recognition molecule affecting apoptotic T-cell clearance. However, the role of properdin in tubular epithelial cells (TECs) at the repair phase post I...

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Bibliographic Details
Main Authors: Yuanyuan Wu, Zinah D. Zwaini, Nigel J. Brunskill, Xinyue Zhang, Hui Wang, Ravinder Chana, Cordula M. Stover, Bin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
apoptosis
inflammation
ischemia–reperfusion injury
phagocytosis
properdin
repair
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.697760/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.697760/full

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