The Effects of CSF Neurogranin and APOE ε4 on Cognition and Neuropathology in Mild Cognitive Impairment and Alzheimer’s Disease

The Effects of CSF Neurogranin and APOE ε4 on Cognition and Neuropathology in Mild Cognitive Impairment and Alzheimer’s Disease

Cerebrospinal fluid (CSF) measurements of neurogranin (Ng) have emerged as a promising biomarker for cognitive decline in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). The apolipoprotein E ε4 (APOE ε4) allele is by far the most consistent genetic risk factor for AD. However, it is no...

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Bibliographic Details
Main Authors: Yulan Fan, Ying Gao, Joseph Therriault, Jing Luo, Maowen Ba, Hua Zhang, the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
apolipoprotein E ε4
mild cognitive impairment
neurogranin
cerebrospinal fluid
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.667899/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2021.667899/full

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