Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

<p>Abstract</p> <p>Background</p> <p>We have identified syndecan-2 as a protein potentially involved in perineural invasion of pancreatic adenocarcinoma (PDAC) cells.</p> <p>Methods</p> <p>Syndecan-2 (SDC-2) expression was analyzed in human norma...

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Bibliographic Details
Main Authors: De Oliveira Tiago, Abiatari Ivane, Raulefs Susanne, Sauliunaite Danguole, Erkan Mert, Kong Bo, Friess Helmut, Michalski Christoph W, Kleeff Jörg
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/11/1/19