In Vivo Validation of Alternative FDXR Transcripts in Human Blood in Response to Ionizing Radiation

In Vivo Validation of Alternative FDXR Transcripts in Human Blood in Response to Ionizing Radiation

Following cell stress such as ionising radiation (IR) exposure, multiple cellular pathways are activated. We recently demonstrated that ferredoxin reductase (FDXR) has a remarkable IR-induced transcriptional responsiveness in blood. Here, we provided a first comprehensive FDXR variant profile follow...

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Bibliographic Details
Main Authors: Lourdes Cruz-Garcia, Grainne O’Brien, Botond Sipos, Simon Mayes, Aleš Tichý, Igor Sirák, Marie Davídková, Markéta Marková, Daniel J. Turner, Christophe Badie
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
nanopore sequencing
biodosimetry
FDXR
alternative transcript
splice variants
ionizing radiation
Online Access:https://www.mdpi.com/1422-0067/21/21/7851

Internet

https://www.mdpi.com/1422-0067/21/21/7851

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