Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers

Abstract Synaptic pathology is a central event in Alzheimer’s disease (AD) and other neurodegenerative conditions, and investigation of synaptic proteins can provide valuable tools to follow synaptic dysfunction and loss in these diseases. Neuroligin-1 (Nlgn1) is a postsynaptic cell adhesion protein...

Full description

Bibliographic Details
Main Authors: Elena Camporesi, Tammaryn Lashley, Johan Gobom, Juan Lantero-Rodriguez, Oskar Hansson, Henrik Zetterberg, Kaj Blennow, Bruno Becker
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Acta Neuropathologica Communications
Subjects:
Online Access:https://doi.org/10.1186/s40478-021-01119-4