Reassessment of Caspase Inhibition to Augment Grafted Dopamine Neuron Survival
One experimental therapy for Parkinson's disease (PD) is the transplantation of embryonic ventral mesencephalic tissue. Unfortunately, up to 95% of grafted neurons die, many via apoptosis. Activated caspases play a key role in execution of the apoptotic pathway; therefore, exposure to caspase i...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2004-04-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/000000004783983972 |