LIMD2 Regulates Key Steps of Metastasis Cascade in Papillary Thyroid Cancer Cells via MAPK Crosstalk

LIMD2 Regulates Key Steps of Metastasis Cascade in Papillary Thyroid Cancer Cells via MAPK Crosstalk

Although papillary thyroid carcinoma (PTC) has a good prognosis, 20–90% of patients show metastasis to regional lymph nodes and 10–15% of patients show metastasis to distant sites. Metastatic disease represents the main clinical challenge that impacts survival rate. We previously showed that LIMD2 w...

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Bibliographic Details
Main Authors: Rodrigo Pinheiro Araldi, Thatiana Correa de Melo, Débora Levy, Dener Madeiro de Souza, Beatriz Maurício, Gabriel Avelar Colozza-Gama, Sergio Paulo Bydlowski, Hongzhuang Peng, Frank J. Rauscher, Janete Maria Cerutti
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
papillary thyroid carcinoma
LIMD2
BRAF V600E
CRISPR/Cas9
epithelial-to-mesenchymal transition
Online Access:https://www.mdpi.com/2073-4409/9/11/2522

Internet

https://www.mdpi.com/2073-4409/9/11/2522

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