Recombinant Clostridium difficile Toxin Fragments as Carrier Protein for PSII Surface Polysaccharide Preserve Their Neutralizing Activity

Recombinant Clostridium difficile Toxin Fragments as Carrier Protein for PSII Surface Polysaccharide Preserve Their Neutralizing Activity

Clostridium difficile is a Gram-positive bacterium and is the most commonly diagnosed cause of hospital-associated and antimicrobial-associated diarrhea. Despite the emergence of epidemic C. difficile strains having led to an increase in the incidence of the disease, a vaccine against this pathogen...

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Bibliographic Details
Main Authors: Maria R. Romano, Rosanna Leuzzi, Emilia Cappelletti, Marta Tontini, Alberto Nilo, Daniela Proietti, Francesco Berti, Paolo Costantino, Roberto Adamo, Maria Scarselli
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Toxins
Subjects:
Clostridium difficile
glycoconjugate
PSII polysaccharide
recombinant toxin fragment
Online Access:http://www.mdpi.com/2072-6651/6/4/1385

Internet

http://www.mdpi.com/2072-6651/6/4/1385

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