DDAH2 (-449 G/C) G allele is positively associated with leukoaraiosis in northeastern China: a double-blind, intergroup comparison, case-control study

DDAH2 (-449 G/C) G allele is positively associated with leukoaraiosis in northeastern China: a double-blind, intergroup comparison, case-control study

Cerebrovascular endothelial dysfunction is involved in the progression of leukoaraiosis. Asymmetric dimethylarginine is a competitive inhibitor of nitric oxide, which is highly expressed in patients with leukoaraiosis. Dimethylarginine dimethylaminohydrolase (DDAH) is a hydrolytic enzyme that is pri...

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Bibliographic Details
Main Authors: Ying Fan, Qiang Gao, Jia-Xin Guan, Lei Liu, Ming Hong, Li Jun, Li Wang, Hai-Feng Ding, Li-Hong Jiang, Bo-Yu Hou, Mei Li, Zhi-Qiang Song, De-Qin Sun, Chao-Qi Yan, Lan Ma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
leukoaraiosis; dimethylarginine dimethylaminohydrolase 2; gene polymorphism; allele; asymmetric dimethylarginine; nitric oxide; endothelial dysfunction; cerebrovascular diseases; clinical trial
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=8;spage=1592;epage=1597;aulast=Fan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=8;spage=1592;epage=1597;aulast=Fan

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