Relationships between Th1 or Th2 iNKT cell activity and structures of CD1d-antigen complexes: meta-analysis of CD1d-glycolipids dynamics simulations.

A number of potentially bioactive molecules can be found in nature. In particular, marine organisms are a valuable source of bioactive compounds. The activity of an α-galactosylceramide was first discovered in 1993 via screening of a Japanese marine sponge (Agelas mauritanius). Very rapidly, a synth...

Full description

Bibliographic Details
Main Authors: Xavier Laurent, Nicolas Renault, Amaury Farce, Philippe Chavatte, Eric Hénon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4222593?pdf=render