Induction of Oligodendrocyte Differentiation and In Vitro Myelination by Inhibition of Rho-Associated Kinase

In inflammatory demyelinating diseases such as multiple sclerosis (MS), myelin degradation results in loss of axonal function and eventual axonal degeneration. Differentiation of resident oligodendrocyte precursor cells (OPCs) leading to remyelination of denuded axons occurs regularly in early stage...

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Bibliographic Details
Main Authors: Carlos E. Pedraza, Christopher Taylor, Albertina Pereira, Michelle Seng, Chui-Se Tham, Michal Izrael, Michael Webb
Format: Article
Language:English
Published: SAGE Publishing 2014-06-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/1759091414538134