The role of PPM1D in cancer and advances in studies of its inhibitors

A greater understanding of factors causing cancer initiation, progression and evolution is of paramount importance. Among them, the serine/threonine phosphatase PPM1D, also referred to as wild-type p53-induced phosphatase 1 (Wip1) or protein phosphatase 2C delta (PP2Cδ), is emerging as an important...

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Bibliographic Details
Main Authors: Wenhong Deng, Jieqing Li, Kimberly Dorrah, Denise Jimenez-Tapia, Brando Arriaga, Qiongyu Hao, Wei Cao, Zhaoxia Gao, Jay Vadgama, Yong Wu
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301463