RNA and DNA bacteriophages as molecular diagnosis controls in clinical virology: a comprehensive study of more than 45,000 routine PCR tests.

Real-time PCR techniques are now commonly used for the detection of viral genomes in various human specimens and require for validation both external and internal controls (ECs and ICs). In particular, ICs added to clinical samples are necessary to monitor the extraction, reverse transcription, and...

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Bibliographic Details
Main Authors: Laetitia Ninove, Antoine Nougairede, Celine Gazin, Laurence Thirion, Ilenia Delogu, Christine Zandotti, Remi N Charrel, Xavier De Lamballerie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3036576?pdf=render