Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?

The current concept of basal ganglia organization and function in physiological and pathophysiological conditions excludes the most numerous cells in the brain, i.e. the astrocytes, present with a ratio of 10:1 neuron. Their role in neurodegenerative condition such as Parkinson’s disease (PD) remain...

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Bibliographic Details
Main Authors: Giselle eCharron, Evelyne eDoudnikoff, Marie-Helene eCanron, Qin eLi, Celine eVega, sebastien eMarais, Jerome eBaufreton, Anne eVital, Stéphane H Oliet, Erwan eBezard
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
rat
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00258/full