DDRs: receptors that mediate adhesion, migration and invasion in breast cancer cells

Discoidin domain receptors (DDRs) are receptor tyrosine kinases that are activated by native collagens and have an important role during cell adhesion, development, differentiation, proliferation, and migration. DDR deregulation is associated with progression of several different cancers. However, t...

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Bibliographic Details
Main Authors: Emmanuel Reyes-Uribe, Nathalia Serna-Marquez, Eduardo Perez Salazar
Format: Article
Language:English
Published: AIMS Press 2015-08-01
Series:AIMS Biophysics
Subjects:
Online Access:http://www.aimspress.com/biophysics/article/359/fulltext.html