The case for inhibiting p38 mitogen-activated protein kinase in heart failure

This minireview discusses the evidence that the inhibition of p38 mitogen-activated protein kinases (p38 MAPKs) maybe of therapeutic value in heart failure. Most previous experimental studies, as well as past and ongoing clinical trials, have focussed on the role of p38 MAPKs in myocardial infarctio...

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Bibliographic Details
Main Authors: Pelin eArabacilar, Michael eMarber
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Pharmacology
Subjects:
p38
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00102/full