Some CSF Kynurenine Pathway Intermediates Associated with Disease Evolution in Amyotrophic Lateral Sclerosis

Some CSF Kynurenine Pathway Intermediates Associated with Disease Evolution in Amyotrophic Lateral Sclerosis

The aim of this study was to evaluate the kynurenine pathway (KP) and amino acids profile, using mass spectrometry, in the cerebrospinal fluid (CSF) of 42 amyotrophic lateral sclerosis (ALS) patients at the diagnosis and 40 controls to detect early disorders of these pathways. Diagnostic and predict...

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Bibliographic Details
Main Authors: Hugo Alarcan, Romane Chaumond, Patrick Emond, Isabelle Benz-De Bretagne, Antoine Lefèvre, Salah-eddine Bakkouche, Charlotte Veyrat-Durebex, Patrick Vourc’h, Christian Andres, Philippe Corcia, Hélène Blasco
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomolecules
Subjects:
amyotrophic lateral sclerosis
kynurenine pathway
tryptophan
amino acids
cerebrospinal fluid
PLS-DA
Online Access:https://www.mdpi.com/2218-273X/11/5/691

Internet

https://www.mdpi.com/2218-273X/11/5/691

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