Mechanisms of Developmental Toxicity of Dioxins and Related Compounds

Mechanisms of Developmental Toxicity of Dioxins and Related Compounds

Dioxins and related compounds induce morphological abnormalities in developing animals in an aryl hydrocarbon receptor (AhR)-dependent manner. Here we review the studies in which 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) is used as a prototypical compound to elucidate the pathoge...

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Bibliographic Details
Main Authors: Wataru Yoshioka, Chiharu Tohyama
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
dioxin
TCDD
malformation
terata
cleft palate
hydronephrosis
prostate
heart
jaw
Online Access:https://www.mdpi.com/1422-0067/20/3/617

Internet

https://www.mdpi.com/1422-0067/20/3/617

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