Integrating Network Pharmacology and Metabolomics Study on Anti-rheumatic Mechanisms and Antagonistic Effects Against Methotrexate-Induced Toxicity of Qing-Luo-Yin

Integrating Network Pharmacology and Metabolomics Study on Anti-rheumatic Mechanisms and Antagonistic Effects Against Methotrexate-Induced Toxicity of Qing-Luo-Yin

Qing-Luo-Yin (QLY) is a traditional Chinese medicine (TCM) formula used to treat Hot Syndrome-related rheumatoid arthritis (RA). Previously, we uncovered partial mechanisms involved in the therapeutic actions of QLY on RA. In this study, we further elucidated its anti-rheumatic mechanisms and invest...

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Bibliographic Details
Main Authors: Jian Zuo, Xin Wang, Yang Liu, Jing Ye, Qingfei Liu, Yan Li, Shao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
Qing-Luo-Yin
rheumatoid arthritis
network pharmacology
metabolomics
nucleotide metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01472/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01472/full

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